How can auto-reply messages be enabled for replies to emails sent by NTO?

The correct option involves using the Reply Mail Management settings page to create a custom response and select the HTML email format for replies. This is an essential feature for organizations that require automated responses to ensure that recipients receive timely acknowledgments for their email inquiries.

When auto-reply messages are set up through the Reply Mail Management settings, they allow the sender to craft a tailored message that reflects the organization's branding and communicates important information, such as expected response times or alternative contacts. Using HTML format adds the flexibility to design visually appealing and effective messages that can enhance recipient engagement.

The approach of creating a custom response facilitates a more personalized interaction, which is vital for maintaining good relationships with clients or customers who reach out via email. This method is straightforward and leverages existing configurations within the email management system to automate replies efficiently.

In contrast, the other options focus on different mechanisms that may not align with the specific requirement of auto-reply for emails sent by NTO, thus making them less suitable for this context.